Investigation in women of childbearing age after renal transplantation: Menstruation, sexual life and birth condition

doi:10.3969/j.issn.2095-4344.2013.05.006

Abstract

Abstract:

BACKGROUND: Theoretically, successful renal transplantation can normalize the menstruation and significantly improve the sexual life of women of childbearing age, and these women can give birth after renal transplantation, but the related domestic reports are rare.
OBJECTIVE: To investigate the menstruation, sexual life and birth condition of fertility age women with different ages and to explore the affecting factors through the homemade questionnaire of menstruation, sexual life and birth condition in women of childbearing age after renal transplantation combined with the quality of life scale and female sexual function index scale.
METHODS: Sixty-eight women of childbearing age who were treated with renal transplantation in the Changzheng Hospital were selected from January 2006 to December 2011. The patients were divided into young group (n=41) and middle aged group (n=27) on the basis of the age, and then the patients in the two groups received the outpatient and telephone follow-up with a homemade questionnaire of menstruation, sexual life and birth condition questionnaire in women of childbearing age after renal transplantation combined with the quality of life scale and female sexual function index scale. The menstruation, sexual life and birth condition of the patients in two groups were observed at 3 years after transplantation and during the blood dialysis stage.
RESULTS AND CONCLUSION: For the menstruation of patients, 54 cases (38 cases in the young group and 16 cases in the middle aged group) were improved at (3.46±1.23) months after transplantation; 11 cases (three cases in the young group and eight cases in the middle aged group) were improved not obviously; and three cases (0 case in the young group and three cases in the middle aged group) suffered deterioration before blood dialysis, and due to the excessive menstrual volume, two cases received curettage surgery and one case received hysteroscopy hemostatic surgery. For the sexual life of the patients, 45 cases (34 cases in the young group and 11 cases in the middle aged group) were improved at (3.43±1.27) months after transplantation; 11 cases (two cases in the young group and nine cases in the middle aged group) were improved not obviously; 12 cases (five cases in the young group and seven cases in the middle aged group) without sexual life after transplantation. For the birth condition of the patients, there were seven cases of pregnancy (five cases in the young group and two cases in the middle aged group) at (30.24±7.86) months after transplantation, and two cases in the young group had children successfully and the other five cases of abortion. The MOS 36-item short-form health survey before and after transplantation showed that the physical function, bodily pain, general health and vitality field score were significantly increased compared with those before transplantation (P < 0.05), and there were no significant differences in emotional function, mental health and social function score before and after transplantations (P > 0.05). Comparison of the female sexual function index before and after transplantation showed that the scores on sexual desire, sexual excitement, vaginal lubrication, orgasm and satisfaction were increased after transplantation; while the pain score was decreased, and the differences were statistically significant (P < 0.05). The results showed that the menstruation and sexual life of the older recipients were not improved obviously, but the pregnancy of the female recipients was feasible and safe under the strict monitoring and control according to the standard seriously conception.

Key words: organ transplantation, renal transplantation, female, hemodialysis, menstruation, sexual life, fertility, the MOS 36-item short-form health survey, female sexual function index scale, survey

CLC Number:

R318

Zuo Fu-jie, Han Shu, Wang Li-ming, Min Min, Feng Xiao-fang, Zhou Mei-sheng, Li Qun. Investigation in women of childbearing age after renal transplantation: Menstruation, sexual life and birth condition[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(5): 797-804.

Figures/Tables 5

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