Chinese Journal of Tissue Engineering Research ›› 2022, Vol. 26 ›› Issue (6): 943-948.doi: 10.12307/2022.182

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A comparative study of imaging parameters and quality of life scores between subtypes of lumbar spondylolisthesis

Li Yuqiao1, Sun Tianwei2, Ma Bin3, Zhou Zhaohong3, Dong Runbei1, Wu Haiyang1    

  1. 1Tianjin Medical University, Tianjin 300121, China; 2Tianjin Medical Union Center, Tianjin 300100, China; 3Nankai University, Tianjin 300071, China
  • Received:2021-03-22 Revised:2021-03-24 Accepted:2021-05-12 Online:2022-02-28 Published:2021-12-08
  • Contact: Sun Tianwei, MD, Chief physician, Tianjin Medical Union Center, Tianjin 300100, China
  • About author:Li Yuqiao, Doctoral candidate, Tianjin Medical University, Tianjin 300121, China
  • Supported by:
    Tianjin Natural Science Foundation, No. 18JCYBJC28200 (to STW); the Scientific Research Project of Tianjin People’s Hospital, No. 2019JZPY02 (to STW)

Abstract: BACKGROUND: Previous studies have reported the comparison of the sagittal parameters of the spine and pelvis between patients with lumbar spondylolisthesis and the normal population, but comparative studies on the differences in imaging parameters between patients with different subtypes of lumbar spondylolisthesis and their impact on the quality of life scores are relatively scarce.  
OBJECTIVE: To analyze the differences in imaging parameters between subtypes of lumbar spondylolisthesis and its relationship with quality of life.
METHODS:  This study retrospectively analyzed 63 patients with lumbar spondylolisthesis. These patients were divided into degenerative lumbar spondylolisthesis group (n=35) and isthmic spondylolisthesis group (n=28). Spine and pelvic imaging parameters, including sagittal vertebral axis, lumbar lordosis, pelvic incidence, pelvic tilt, sacral slope, pelvic incidence-lumbar lordosis matching, lumbar 1 plumb line, upper lumbar curve, and lower lumbar curve, and functional score (health related quality of life score) were analyzed between the two groups. The protocols were in accordance with the relevant ethical requirements of Declaration of Helsinki and Tianjin People’s Hospital. The patients signed informed consent.  
RESULTS AND CONCLUSION: (1) In the study of preoperative imaging parameters, sagittal vertebral axis was significantly higher in the degenerative lumbar spondylolisthesis group than that in the isthmic spondylolisthesis group. Pelvic tilt, lumbar lordosis, upper lumbar curve, and lower lumbar curve were significantly lower in the degenerative lumbar spondylolisthesis group than those in the isthmic spondylolisthesis group (all P < 0.05 or P < 0.01). The other imaging indications showed no significant differences between the two groups. (2) Pelvic tilt was significantly lower in patients with visual analogue scale (low back pain) score ≤3 than that in patients scoring > 3 (P=0.026, P=0.047). (3) There was no significant difference in imaging indexes between the two groups of patients with preoperative Oswestry disability index > 40 and those with Oswestry disability index ≤40. (4) The results have shown that there are significant differences in sagittal biomechanics between degenerative lumbar spondylolisthesis and isthmic fissure lumbar spondylolisthesis. Pelvic tilt was significantly lower in patients with visual analogue scale (low back pain) score ≤3 than that in patients scoring > 3.

Key words: spondylolisthesis, degenerative spondylolisthesis, isthmic spondylolisthesis, sagittal parameters of spine and pelvis, health-related quality of life score, lumbar lordosis, pelvic tilt, pelvic incidence-lumbar lordosis matching

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