Chinese Journal of Tissue Engineering Research ›› 2019, Vol. 23 ›› Issue (22): 3451-3455.doi: 10.3969/j.issn.2095-4344.1271

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Bracketless invisible orthodontic appliance for treating adult periodontal disease

Yang Baokuan1, 2, Huang Rui1, Shi Xinghui1
  

  1. 1Third Outpatient Department, Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing 210014, Jiangsu Province, China; 2Jiangsu Provincial Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing 210000, Jiangsu Province, China
  • Received:2019-03-13
  • Contact: Huang Rui, Physician, Third Outpatient Department, Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing 210014, Jiangsu Province, China
  • About author:Yang Baokuan, Master, Attending physician, Third Outpatient Department, Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing 210014, Jiangsu Province, China; Jiangsu Provincial Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing 210000, Jiangsu Province, China

Abstract:

BACKGROUND: Bracketless invisible orthodontic appliance has been shown to be available for adult periodontal disease.
OBJECTIVE: To compare the treatment efficacy between bracketless invisible orthodontic appliance and traditional method in adult periodontal disease.
METHODS: One hundred and twenty cases of periodontal disease admitted at Affiliated Stomatological Hospital of Nanjing Medical University from January 2013 to August 2016 were enrolled, and randomized into observation group (n=60, bracketless invisible orthodontic appliance) and control group (n=60, traditional method). The gingival index, probing depth, sulcus bleeding index and plaque index before and after therapy were detected and the curative effect was assessed. The levels of C-reactive protein, tumor necrosis factor-α, interleukin-2 and interleukin-6 in the gingival crevicular fluid were measured. The study was approved by the Ethics Committee of Affiliated Stomatological Hospital of Nanjing Medical University, approval No. 201302036.
RESULTS AND CONCLUSION: (1) The plaque index after therapy in the observation group was significantly lower than that in the control group (P < 0.05). The gingival index, probing depth, and sulcus bleeding index showed no significant difference between two groups (P > 0.05). (2) The total effective rate in the observation group (93.3%) was significantly higher than that in the control group (80.0%) (P < 0.05). (3) The levels of C-reactive protein, tumor necrosis factor-α, and interleukin-6 in the gingival crevicular fluid in the observation group were significantly lower than those in the control group (P < 0.05), and the level of interleukin-2 was significantly higher than that in the control group (P < 0.05). (4) In summary, the efficacy of bracketless invisible orthodontic appliance for treating adult periodontal disease is exact, and can effectively reduce the levels of inflammatory factors.

Key words: bracketless invisible orthodontic appliance, periodontal disease, probing depth, sulcus bleeding, tumor necrosis factor-α, interleukin-2, C-reactive protein

CLC Number: 

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R459.9