Chinese Journal of Tissue Engineering Research ›› 2019, Vol. 23 ›› Issue (16): 2529-2537.doi: 10.3969/j.issn.2095-4344.1210

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Three-dimensional models of Lenke3 type adult idiopathic scoliosis simulating orthopedic surgeries  

Xin Daqi1, Yang Xuejun1, Wang Guoqiang1, Xiao Yulong1, Hu Zhenming2, Xing Wenhua1, Zhao Yan1, Fu Yu1, Zhu Yong1, Bai Xianming1   

  1. 1Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongolia Autonomous Region, China; 2Department of Orthopedics, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • Online:2019-06-08 Published:2019-06-08
  • Contact: Wang Guoqiang, Chief physician, Master’s supervisor, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongolia Autonomous Region, China
  • About author:Xin Daqi, MD, Associate chief physician, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongolia Autonomous Region, China
  • Supported by:

    the Natural Science Foundation of Inner Mongolia Autonomous Region, No. 2016MS08141 (to WGQ)

Abstract:

BACKGROUND: Due to diversity and stiffness of adult idiopathic scoliosis, individualized patients need orthopedics and individualized design, which affect the surgical safety and prognosis. Making the surgical scheme should consider the factors affecting the orthopedics of thoracolumbar scoliosis.

OBJECTIVE: To stimulate different surgical methods on the corrected model of Lenke3 type adult idiopathic scoliosis, and to understand the stress of pedicle screw and orthopedic efficacy. 
METHODS: In optimized finite element model of Lenke3 type adult idiopathic scoliosis, finite element operations were simulated separately, including simulating different combinations: Case1:posterior vertebral key pedicle screw and posterior capsular release surgery; Case2: posterior vertebral key pedicle screw and posterior capsular release surgery as well as anterior release for thoracic scoliosis; Case3: posterior vertebral key pedicle screw and posterior capsular release surgery and anterior release for lumbar scoliosis; Case4: posterior vertebral key pedicle screw and posterior capsular release surgery and anterior release for thoracolumbar side convex; Case5: posterior vertebral key pedicle screwing and posterior capsular release surgery and anterior thoracolumbar scoliosis release surgery. The effectiveness and the biomechanical characteristics of three-dimensional orthopedics of different surgical programs in patients with Lenke3 type adult idiopathic scoliosis.
RESULTS AND CONCLUSION: (1) Five surgical schemes were completed successfully on the optimized finite element model. (2) The maximum stress value in each pedicle screw was lower than the threshold of the screw itself, which concentrated on the L4 down side. (3) The orthopedic rates of thoracic spine scoliosis in Case1-5 were 63.9%, 59.9%, 67.6%, 61.5%, 66.4%, respectively, and orthopedic rates of lumbar scoliosis were 39.1%, 32.2%, 36.8%, 42.9%, 49.3%, respectively. (4) The experimental results of thoracic release surgery in Case3 and 5 showed the effectiveness of its orthopedics have no significant increase, but the stress of their respective pedicle screw structure would be significantly reduced. The results of Case4 and 5 showed its stresses in the vertebral body derotation and lumbar/thoracic screws are much better than other groups. (5) These experimental results provide quantitative indicators for finite element biomechanical study on adult idiopathic scoliosis, and subsequently provide some theoretical support to predict therapeutic effect of orthopedic surgery and formulate clinical programs for patient with Lenke3 type of adult idiopathic scoliosis.

Key words: adult idiopathic scoliosis, spine, lumbar release, finite element analysis, key vertebrae, biomechanics, pedicle screw, surgical simulation

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