Stress in tendon healing

doi:10.3969/j.issn.2095-4344.2015.29.024

Abstract

Abstract:

BACKGROUND: As mechanical load-bearing tissues, tendons have unique biomechanical characteristics. Mechanical loading is necessary in tendon development, and the tendon can alter its structure and biological behaviors in response to the various mechanical loading conditions.
OBJECTIVE: To fully understand the healing process and biomechanical properties of the damaged tendon so as to know the researching progress in the role of stress in the tendon healing process.
METHODS: An electronic search of Chinese Biomedical Literature Database and PubMed databases was done for collection of reviews and papers addressing stress effects on tendon healing, and then we analyzed the role of stress in the healing process of tendon from the micro and macro levels.
RESULTS AND CONCLUSION: Totally 59 relevant articles were enrolled. Tendon is sensitive to stress, and it can change its structure and biological reaction in response to different stress loadings. Proper stress stimulus to the tendon is necessary to the tendon development and healing. How to achieve a good balance between the lowest (resulting in alienation effect) and the highest stress loadings (resulting in minimally invasive injury) during the clinical tendon healing is a challenge. At present the treatment of tendon injuries is still a huge challenge to clinicians, and the vast majority of tendon injuries belong to tissue healing.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: Stress, Mechanical, Tendon Injuries, Tissue Adhesions

CLC Number:

R318

Guo Wen, Wang Ji-hong, Wen Shu-zheng, Xu Peng-cheng. Stress in tendon healing [J]. Chinese Journal of Tissue Engineering Research, 2015, 19(29): 4715-4720.

Figures/Tables 1

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