Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (21): 3377-3381.doi: 10.3969/j.issn.2095-4344.2015.21.018

Previous Articles     Next Articles

Thoracolumbar spinal reconstruction with titanium mesh implantation combined with internal fixation after tumor resection: stability and biocompatibility 

Wang Fan-dong, Zhang Zhi, Zheng Jia-zhuang, Chen Yu, Cai Qi-lin   

  1. Second Orthopaedics Ward, Orthopedics Center, the Central Hospital of Suining City, Suining 629000, Sichuan Province, China
  • Online:2015-05-21 Published:2015-05-21
  • Contact: Zhang Zhi, Second Orthopaedics Ward, Orthopedics Center, the Central Hospital of Suining City, Suining 629000, Sichuan Province, China
  • About author:Wang Fan-dong, Attending physician, Second Orthopaedics Ward, Orthopedics Center, the Central Hospital of Suining City, Suining 629000, Sichuan Province, China

Abstract:

BACKGROUND: Clinical resection of thoracolumbar spinal tumor has a great impact on the spinal stability. Positive internal fixation is required clinically in order to maintain the spinal stability. The use of titanium mesh implantation can provide a firm internal fixation following resection of tumors.
OBJECTIVE: To explore the spinal stability undergoing titanium mesh implantation with internal fixation following thoracolumbar tumor resection.
METHODS: Twenty-four patients with thoracolumbar tumor admitted at the Central Hospital of Suining City from September 2013 to September 2014 were randomly selected and given tumor resection followed by titanium mesh implantation with internal fixation. After treatment, patients were followed up for 1-12 months to observe and analyze the neural functional recovery and spinal stability of the patients.
RESULTS AND CONCLUSION: All the 24 patients successfully completed the operation treatment, and there was no case of death at the end of follow-up. During the follow-up, patient’s clinical symptoms and neural function were significantly relieved, and Frankel classification was significantly improved after treatment. Regular X-ray examination showed that there was no change in the position of titanium mesh and anterior internal fixation system. There was also no titanium mesh collapse, internal fixation fracture and loosening, and the spinal stability was still excellent. These findings indicate that patients were not changed, and did not appear because the amount of loose, good spinal stability. Resection of thoracolumbar tumors showed that the thoracolumbar spinal reconstruction with titanium mesh implantation combined with internal fixation following tumor resection can obtain good clinical effect and excellent biocompatiblity.
 

中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程

Key words: Titanium, Spine, Neoplasms

CLC Number: