Feasibility of medical glue for open wound of the frontal plane in children

doi:10.3969/j.issn.2095-4344.2015.21.013

Abstract

Abstract:

BACKGROUND: Medical glue as a biological hemostatic material shows a good diffusivity in body fluids and blood, and has a rapid polymerization reaction, which plays an ideal hemostatic effect and promotes wound healing.
OBJECTIVE: To investigate the clinical value of medical glue as a hemostatic material in the open wound of the frontal plane in children.
METHODS: Totally 1 218 children with open wounds of the frontal plane treated with medical glue were enrolled as observation group, and another 600 children with open wounds of the frontal plane treated with silk sutures as control group. Wound healing time, postoperative wound bleeding, suture reaction, pigmentation and scar hyperplasia were compared between the two groups.
RESULTS AND CONCLUSION: Compared with the control group, the operative time, blood loss and wound healing time were all less in the observation group (P < 0.05), and the effective bleeding rate was higher in the
observation group (P < 0.05). Stage I wound healing occurred in 1 215 cases of the observation group, and 586 cases of the control group. At the end of 12-month follow-up, healed scar formed with no knot scar and needle scar, the skin color was similar and cosmetic results were good in the observation group; in the control group, there were more obvious scars, visible knot and needle scars, and erythema, induration and hypertrophic scars were found around the most wounds. The medical glue for open wounds of the frontal plane in children has good biocompatibility and cosmetic results, which is safe and convenient in clinical use.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Hemostatic Techniques, Child, Cicatrix

CLC Number:

R318

Li Xian-ling, Lu Shou-yan, Liu Ting-ting. Feasibility of medical glue for open wound of the frontal plane in children [J]. Chinese Journal of Tissue Engineering Research, 2015, 19(21): 3350-3354.

Figures/Tables 1

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