Changes of renal function of patients with first unilateral total knee arthroplasty

doi:10.3969/j.issn.2095-4344.2013.17.004

Abstract

Abstract:

BACKGROUND: Implanting prosthesis system during operation, perioperative haemodynamics changes and drugs may affect the renal function of patients receiving total knee arthroplasty.
OBJECTIVE: To dynamically assess the effect of relative treatment on the renal function in the perioperative period of total knee arthroplasty.
METHODS: Forty-two patients with total knee arthroplasty were included. The serum creatinine, cystatin C and microalbuminuria levels before and after total knee arthroplasty were detected, and then renal function before and after replacement were compared.
RESULTS AND CONCLUSION: All of the total knee arthroplasty operations were successful in 42 patients, and no oliguria, anuria, amount urinary protein and renal failure or other serious kidney complications were observed within 1 month after total knee arthroplasty. There was no change in serum creatinine level, so was cystatin C in 1 week after total knee arthroplasty, but the cystatin C level was decreased significantly at 1 month after the operation. The microalbuminuria concentration was increased at 1 day after total knee arthroplasty, and began to descent on day 3, and the microalbuminuria concentration at 7 days and 1 month after total knee arthroplasty was decreased when compared with that before operation. Total knee arthroplasty only caused mild damage to patients’ renal function, while the average level of renal function was improved at 1 month later. To the patients who receive the unilateral total knee arthroplasty for the first time, active appropriate clinical treatment may alleviate the kidney damage.

Key words: bone and joint implants, artificial prosthesis, total knee arthroplasty, knee joint replacement, prosthesis, serum creatinine, cystatin C, renal function, microalbuminuria, renal failure, hemodynamics, kidney

CLC Number:

R318

Zhang Peng, Liu Jun, Duan Yuan-hui, Long Gang. Changes of renal function of patients with first unilateral total knee arthroplasty[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(17): 3065-3072.

Figures/Tables 7

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