Abstract:

BACKGROUND: Sirolimus-eluting stent is an effective prevention measure for restenosis after coronary stent implantation. It is unclear whether there is a difference between domestic and imported scaffolds.
OBJECTIVE: To compare the effect and safety of biodegradable polygmer stents (EXCEL) made in China and imported durable polymer stents (Cypher) in coronary revascularization.
METHODS: A cohort of 259 consecutive patients with coronary arterial disease was registered. The patients were categorized into EXCEL group (n=130) and Cypher group (n=129).
RESULTS AND CONCLUSION: 256 of 259 patients completed a follow-up visit, and 3 patients lost including 1 in the EXCEL group and 2 in the Cypher group with a lost rate of 1%. There were 2 cases of adverse cardiovascular events in the EXCEL group and 3 in the Cypher group. But there was no significant difference between the two groups (P > 0.05). No restenosis occurred during the follow-up. It was observed that the survival rate without main adverse cardiovascular events was 98.8% and the incidence of sub-acute thrombosis was 1.56% at 18 months after stent implantation. Both of EXCEL and Cypher stents are safe and reliable in coronary revascularization.