Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (37): 6991-6994.doi: 10.3969/j.issn.1673-8225.2010.37.036

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Defects and repair of articular cartilage

Zou A-peng, Song Zhen, Lan Zhong-yu, Bai Xi-zhuang   

  1. Department of Orthopaedics, the First Hospital of China Medical University, Shenyang  110001, Liaoning Province, China
  • Online:2010-09-10 Published:2010-09-10
  • Contact: Bai Xi-zhuang, Doctor, Doctoral supervisor, Chief physician, Professor, Department of Orthopaedics, the First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China zpmhh@sina.com
  • About author:Zou A-peng★, Studying for master’s degree, Department of Orthopaedics, the First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China Yantaiap@yahoo.com.cn
  • Supported by:

    he Science and Technology Foundation of Liaoning Province, No. 2007225015-1*

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Abstract:

BACKGROUND: Articular cartilage has a poor intrinsic capacity for healing, once damaged from trauma or degeneration, it is hard to repair.
OBJECTIVE: To concisely describe the common current treatment of articular cartilage defects and the future trend.
METHODS: A search across the databases of PubMed (January 1995 to June 2010) was performed, with key words of “articular cartilage, cartilage defects, treatment”. The language was limited for English.The repetitive studies or unrelated to papers the objective were excluded. A total of 32 papers were included in this study.
RESULTS AND CONCLUSION: Microfracture, autologous osteochondral transplantation, osteochondral allograft transplantation, and autologous chondrocyte implantation were common used for repairing articular cartilage defects. Usually, these strategies could relieve clinical symptoms effectively, but there are problems need to be solved. Compared with those techniques, cartilage tissue engineering is a new strategy for cartilage repair emerging in recent years, and many studies about it are still ongoing.

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