Abstract:

BACKGROUND: Plenty of free radicals were produced by skeletal muscle after acute exercise, which disturbs the balance between oxidizing agent and antioxidant, leads to skeletal muscle fatigue, muscle dysfunction and damage, eventually decreases the motor ability. Tea polyphenols is a polyphenolic compound extracted from tea and has strong antioxidative activities, which is a natural antioxidant with highly effective and low toxicity.
OBJECTIVE: To intervene the motility damage on skeletal muscle tissue, and to observe the protective effect of tea polyphenols on oxidative injure.
METHODS: Thirty health male Sprague Dawley rats were randomly divided into the control, exercise and tea polyphenols groups. At 1 week after adding tea polyphenols in the tea polyphenols group, rats were prepared for acute exhausted exercise models by exhaustive swimming. The exhaustive duration was recorded, and the levels of malonaldehyde (MDA), super oxide dimutese (SOD), glutathione peroxidase (GSH-Px) and total antioxidative capacity (T-AOC) in skeletal muscle after immediately acute exhausted exercise were measured.
RESULTS AND CONCLUSION: Exhaustive exercise could step up the content of MDA, and significantly decrease SOD, GSH-Px and TAC in rats’ skeletal muscle tissues. While tea polyphenols could decrease MDA levels, increase the SOD, GSH-Px and TAC levels and prolong exhaustive duration of rats. Accordingly, after exhaustive exercise, skeletal muscle tissues were injured by free radicals’ attack. Tea polyphenols can prevent oxdiative damage and improve the ability of exercise.