Chinese Journal of Tissue Engineering Research ›› 2017, Vol. 21 ›› Issue (19): 2980-2985.doi: 10.3969/j.issn.2095-4344.2017.19.005
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Wang Jing-xu, Gong Shu-yi, Wu Bo
Online:
2017-07-08
Published:
2017-08-10
Contact:
Wu Bo, Master, Chief physician, Doctoral supervisor, Department of Spine Surgery, Orthopedic Hospital of Shenyang, Shenyang 110044, Liaoning Province, China
About author:
Wang Jing-xu, Chief physician, Department of Spine Surgery, Orthopedic Hospital of Shenyang, Shenyang 110044, Liaoning Province, China
CLC Number:
Wang Jing-xu, Gong Shu-yi, Wu Bo. Efficacy and safety of K-rod dynamic stabilization system in the repair of lumbar degenerative diseases: study protocol for a prospective, self-controlled, clinical trial[J]. Chinese Journal of Tissue Engineering Research, 2017, 21(19): 2980-2985.
试验于2013年3月开始收集样本,于2016年3月完成样本收集,预计到2018年3月完成最终实验的数据分析,目前的部分实验结果如下: 2.1 基线资料 患者平均年龄49岁,年龄32-76岁,平均病史10年,女43例,男24例。患者42例(63%)为首次进行K-rod固定,患者25例(37%)以前接受过相同和/或相邻节段的融合减压修复。 2.2 疗效随访结果 患者术前中位平均Oswestry功能障碍指数为53.4%(31%-80%),固定后中位平均得分为28.4%(0%-55%),而在末次随访时评分为27.3% (0%-70%),和术前相比差异有显著性意义(P < 0.01)。 患者背部疼痛目测类比评分从术前的63.2分(30-100分)减少到固定后的33.1分(2-75分),并最终在末次随访时降低到31.9分(0-70分),和术前相比差异有显著性意义(P < 0.01)。 患者术前与固定后各时间点椎间盘间隙与椎体高度的比值及腰椎前凸角差异无显著性意义(P > 0.05),见表3。"
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