Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (53): 8549-8553.doi: 10.3969/j.issn.2095-4344.2015.53.004

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Total hip arthroplasty repairs ankylosing spondylitis-associated hip joint lesion based on the biological level: 2-year follow-up

Ding Liang-jia1, Liu Ying-li2, Liu Xiao-min1, Ma Gang1, Liu Chang-lu1   

  1. 1Department of Joint Surgery, 2Department of Rehabilitation, the Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongelia Autonomous Region, China
  • Received:2015-10-01 Online:2015-12-24 Published:2015-12-24
  • Contact: Liu Ying-li, Department of Rehabilitation, the Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongelia Autonomous Region, China
  • About author:Ding Liang-jia, Master, Attending physician, Department of Joint Surgery, the Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongelia Autonomous Region, China

Abstract:

BACKGROUND: Due to the continuous development of medical technology and prosthetic material study, patients with ankylosing spondylitis-associated hip joint lesion are often treated with artificial total hip arthroplasty. Because the majority patients of this kind of disease are young patients, it is of great importance for the patients’ life quality through maximizing the recovery of hip function, restoring the biomechanical balance of spine, pelvis and hip joint and prolonging the life of hip joint.
OBJECTIVE: To observe the repair effect of total hip arthroplasty in treatment of ankylosing spondylitis-associated hip joint lesion based on the biological level.
METHODS: Totally 60 patients with ankylosing spondylitis-associated hip joint lesion who received the treatment

 

at Department of Joint Surgery, the Second Affiliated Hospital of Inner Mongolia Medical University from December 2010 to December 2014 (including 2 years of follow-up) were selected and conducted total hip arthroplasty using biological type total hip prosthesis. During 2 years of follow-up, hip activity (total activity, flexion and extension, adduction, abduction, internal rotation, external rotation), hip Harris score, pain visual analog scale score, quality of life of patients were observed, counted and comparatively analyzed before replacement and in the final follow-up. 
RESULTS AND CONCLUSION: The hip joint activity and other various indexes of patients in the final follow-up significantly recovered compared with before treatment (P < 0.05). Before treatment, the hip joint pain of patients was severe, the function and the quality of life were poor, however, in the final follow-up, the pain of patients was obviously relieved, hip function effectively recovered and quality of life improved significantly, the differences were statistically significant (P < 0.05). These results suggest that the application of total hip arthroplasty by using biological type total hip prosthesis on patients with ankytosing spondylitis-associated hip joint lesion can effectively restore physiological and anatomical structure of the hip joint, restore the function and activity of hip joint, relieve pain, and improve the quality of life.  

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