Polypropylene patch repairs anterior pelvic organ dysfunction in older women patients

doi:10.3969/j.issn.2095-4344.2015.52.017

Abstract

Abstract:

BACKGROUND: The patch materials, originally applied in the reconstruction and repair of abdominal hernia, have been successfully applied in the vagina surgery; thus, it has been gradually generalized in gynecological pelvic floor reconstruction.
OBJECTIVE: To analyze the clinical effect of polypropylene patch in older female patients with anterior pelvic organ reconstruction.
METHODS: Totally 24 older female patients with stage III, IV anterior pelvic floor dysfunction were enrolled. The individual treatment was formulated according to the wishes of patients, of which 12 patients underwent anterior pelvic organ reconstruction using polypropylene patch (test group), and 12 patients underwent the simply modified vaginal repair treatment (control group). Patients were followed up for 12 months after repair. The clinical symptom remission, wound healing, pelvic organ prolapse staging and subjective disability index scores were observed.
RESULTS AND CONCLUSIONS: After repair, the clinical symptoms in these two groups were significantly alleviated, and there was no infection, poor wound healing and other adverse reactions. At 12 months of follow-up, the subjective disability index scores in these two groups were all significantly lower than those before repair (P < 0.05); moreover, these scores were significantly lower in the test group than the control group (P < 0.05). There were eight cases of pelvic organ prolapse staging I, four cases of pelvic organ prolapse staging II in the test group; seven cases of pelvic organ prolapse staging I, two cases of pelvic organ prolapse staging II, two cases of pelvic organ prolapse staging III and one case of pelvic organ prolapse staging IV in the control group. The degree of organ prolapse in the test group was lower than that in the control group (P < 0.05). These results demonstrate that polypropylene patch repair used in older female anterior pelvic organ reconstruction is safe and effective, and leads to a low recurrence rate.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

CLC Number:

R318

Zhang Xiao-yue. Polypropylene patch repairs anterior pelvic organ dysfunction in older women patients[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(52): 8455-8460.

Figures/Tables 5

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