Artificial cervical disc prosthesis and zero-profile interbody fixation and fusion system for cervical disease: 2-year follow-up

doi:10.3969/j.issn.2095-4344.2015.22.012

Abstract

Abstract:

BACKGROUND: Artificial cervical disc prosthesis simulates range of motion and buffer shock function of normal intervertebral discs. Clinical experiments verify that artificial cervical disc prosthesis material has good biocompatibility and mechanical characteristics.
OBJECTIVE: To evaluate artificial cervical disc replacement and zero-profile interbody fixation and fusion system for multilevel cervical disease in 2-year follow-up.
METHODS: Artificial cervical disc replacement and zero-profile interbody fixation and fusion system were used to
treat 42 patients with multilevel cervical disease. The patient presented typical symptoms and signs of spinal cord or nerve root compression. There were 18 cases of cervical myelopathy, 15 cases of nerve root cervical spondylosis and 10 cases of mixed type of cervical spondylosis. After treatment, mean operation time, blood loss and reoperation rate were measured. Postoperative complications, disability index of neck function, visual analog scale, function unit range of corresponding surgery segments of the cervical spine, Cobb angle of C₂-C₇vertebral body, range of motion of adjacent segment of proximal and distal vertebral bodies were observed and clinical outcomes were evaluated.
RESULTS AND CONCLUSION: All cases finished the operation and were scored at various time points. After treatment, radiating pain of shoulder and neck and upper extremity were remarkably lessened. Numbness and sensory loss symptoms disappeared obviously. Quality of life elevated noticeably. Visual analog scale and the disability index of neck function score were decreased in final follow-up compared with pre-treatment (P < 0.001). C₂-C₇vertebrae Cobb angle, FSU angle, range of motion of proximal surgery adjacent segment and range of motion of the distal surgery adjacent segment were elevated compared with pre-treatment (P < 0.001). These data indicate that cervical spondylosis was improved after treatment. Each index of cervical spondylosis after artificial cervical disc replacement and zero-profile interbody fixation and fusion system was reconstructed to different degrees.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Cervical Vertebrae, Internal Fixators, Spinal Fusion, Biocompatible Materials

CLC Number:

R318

Dong Zhen-yu, Chu Ge, Huang Yi-fei, Yuan Feng-yun. Artificial cervical disc prosthesis and zero-profile interbody fixation and fusion system for cervical disease: 2-year follow-up [J]. Chinese Journal of Tissue Engineering Research, 2015, 19(22): 3503-3507.

Figures/Tables 2

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中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程