Abstract:

BACKGROUND: At present, the common filling materials used to correct secondary unilateral cleft lip nasal deformity include conchae cartilage, costal cartilage, Medpor implants, expanded polytetrafluoroethylene (ePTFE), allogenic acellular dermal matrix.
OBJECTIVE: To analyze the therapeutic effects of comprehensive procedures with allogenic acellular dermal matrix or ePTFE for secondary unilateral cleft lip nasal deformity.
METHODS: Thirty-six patients with secondary unilateral cleft lip nasal deformity were enrolled, including 19 males and 17 females, aged 15-32 years. Allogenic acellular dermal matrix (n=22) or ePTFE (n=14) was used to correct nasal base collapse deformities. Anthropometry method was employed to make measurements. Fixed-point measurement was performed based on patient’s pictures before and after correction. Long-term effects of these two kinds of filling materials were analyzed and assessed objectively and quantitatively.
RESULTS AND CONCLUSION: After the follow-up of 6 months, all the patients were satisfied with their results, and no infection and no exposure occurred. The treatment effect of the allogenic acellular dermal matrix group was excellent in 16 cases and good in 6 cases; there were 10 cases of excellent and 4 cases of good in the ePTFE group. The objective indicators in the two groups were all improved at 6 months after correction (P < 0.05), but there was no difference between the two groups (P > 0.05). These findings indicate that allogenic acellular dermal matrix or ePTFE is useful to correct secondary unilateral cleft lip nasal deformity.