Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (17): 2672-2676.doi: 10.3969/j.issn.2095-4344.2015.17.009

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Artificial cervical disc replacement: range of motion of replacement segment and degeneration of adjacent segments

Chen Xuan-yu1, 2, Wu Ji1, Zheng Chao1, Huang Rong-rong1, Cui Yu-ming1, Shang Yong1, Fan Heng-hua1,  Yu Pan-feng1, Zhao Xu-hong1, Chu Dong1   

  1. 1Air Force General Hospital of Chinese PLA, Beijing 100149, China; 2Dalian Medical University, Dalian 116044, Liaoning Province, China
  • Online:2015-04-23 Published:2015-04-23
  • Contact: Wu Ji, M.D., Chief physician, Air Force General Hospital of Chinese PLA, Beijing 100149, China
  • About author:Chen Xuan-yu, Master, Physician, Air Force General Hospital of Chinese PLA, Beijing 100149, China; Dalian Medical University, Dalian 116044, Liaoning Province, China

Abstract:

BACKGROUND: In recent years, artificial cervical disc replacement surgery as a new method for the treatment of cervical disease has gradually been accepted and understood, but relevant complications have gradually attracted attention.

OBJECTIVE: To investigate the clinical outcomes of artificial cervical disc replacement in the treatment of cervical disease and the range of motion of the replacement segment.
METHODS: A total of 25 patients with artificial cervical disc replacement in the treatment of cervical spondylosis, who were treated in the Department of Orthopedics, Air Force General Hospital of Chinese PLA from August 2006 to April 2012, were enrolled in this study, including 15 males and 10 females, aged 31-76 years, averagely 51.04 years. There were 6 cases of double segments and 19 cases of single segment. They were followed up for 24 to 93 months. Clinical results were assessed using the Japanese Orthopaedic Association score, cervical dysfunction index and pain visual analog scale scores. Imaging was used to observe range of motion, cervical curvature, heterotopic ossification, and degeneration of adjacent segments.
RESULTS AND CONCLUSION: Neurological function in all patients was improved to different degrees. One case suffered from mild heterotopic ossification, but no clinical symptoms were found. No significant difference in range of motion of surgical segment, and range of motion of upper and lower adjacent segments was detected between pre-replacement and final follow-up results (P > 0.05). No significant difference in range of motion of C2-C7 was found between pre-replacement and final follow-up results (P > 0.05). Japanese Orthopaedic Association score, cervical dysfunction index and pain visual analog scale scores were significantly improved during final follow-up compared with pre-replacement (P < 0.05). These results indicated that artificial cervical disc replacement in the treatment of cervical disease can achieve better clinical efficacy, can keep the range of motion of replacement segment and avoid the accelerated degeneration of adjacent segments.

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程


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Key words: Cervical Vertebrae, Intervertebral Disk, Follow-Up Studies

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