Therapies for early avascular necrosis of the femoral head: core decompression with quadratus femoris implantation is better than core decompression with bone paste implantation

doi:10.3969/j.issn.2095-4344.2015.12.003

Abstract

Abstract:

BACKGROUND: Core decompression may provide insufficient support for the subchondral bone in the treatment of early avascular necrosis of the femoral head and increase the risk of fracture and collapse. Quadratus femoris implantation cannot only provide good biological support, but also promote the revascularization at necrotic regions, thus repairing the necrosis of femoral head.
OBJECTIVE: To compare the clinical effects of core decompression with bone paste implantation and core decompression with quadratus femoris implantation on early and middle-stage avascular necrosis of the femoral head.
METHODS: Eighty-three patients with early avascular necrosis of the femoral head (92 hips) admitted at the Department of Orthopedics, the First Affiliated Hospital of Zhengzhou University, China, from January 2009 to January 2012 were enrolled and divided into groups of core decompression with bone paste implantation (46 cases, 49 hips) and core decompression with quadratus femoris implantation (37 cases, 43 hips) that were respectively injected with bone meal and autogenous bone and osteoinductive materials.
RESULTS AND CONCLUSION: All involved patients were followed up. After 1 year of treatment, Harris scores in the two groups were both increased (P < 0.05). But the Harris score of core decompression with bone paste implantation group was lower than that of core decompression with quadratus femoris implantation group (P < 0.05). After 3 years of treatment, X-ray scores in the core decompression with quadratus femoris implantation group were significantly higher than those in the core decompression with bone paste implantation group (P < 0.05). These findings indicate that compared with core decompression with bone paste implantation, core decompression with quadratus femoris implantation is better to prevent femoral head collapse, improve hip function and delay the process of osteonecrosis of the femoral head.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: Femur Head Necrosis, Bone Transplantation, X-Ray Absorption Spectroscopy, Hip Joint

CLC Number:

R318

Meng Fei, Wang Jue, Qiu Ru-biao, Yuan Lian-jing, Tang Qian. Therapies for early avascular necrosis of the femoral head: core decompression with quadratus femoris implantation is better than core decompression with bone paste implantation[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(12): 1817-1821.

Figures/Tables 3

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