Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (3): 445-449.doi: 10.3969/j.issn.2095-4344.2015.03.021

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Laser epithelial keratomileusis for the treatment of refractive errors after cataractlens implantation: a stability evaluation

Wei Fen, Ai Ming   

  1. Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 437300, Hubei Province, China
  • Online:2015-01-15 Published:2015-01-15
  • Contact: Ai Ming, M.D., Chief physician, Professor, Doctoral supervisor, Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 437300, Hubei Province, China
  • About author:Wei Fen, Associate chief physician, Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 437300, Hubei Province, China

Abstract:

BACKGROUND: After cataract extraction and intraocular lens implantation, some patients still appear to suffer from refractive errors to varying degrees. In this case, excimer laser epithelial keratomileusis or excimer laser in situ keratomileusis can be used for correction of refractive errors.

OBJECTIVE: To observe the therapeutic effect of excimer laser epithelial keratomileusis on the treatment of residual refractive errors after cataract extraction and intraocular lens implantation.
METHODS: Thirty-eight patients with refractive errors (45 eyes) who had received cataract extraction and intraocular lens implantation were enrolled, including 22 males and 16 females. Patient’s age was 24-74 years, and the central corneal thickness ranged 490-590 μm. Before laser epithelial keratomileusis, the uncorrected visual acuity and corrected visual acuity were 0.1-0.3 and 0.6-1.0, respectively. The uncorrected visual acuity, best corrected visual acuity, diopter, and intraocular pressure were observed at 12 months after correction.
RESULTS AND CONCLUSION: Most of the patients had foreign body sensation, pain and other symptoms of eye irritation at 3-6 postoperative hours, and then presented with eye pain, photophobia, tearing and other symptoms of corneal irritation with 2 days after surgery. The corneal epithelium healed basically at 7 days after surgery, and the vision recovered to top after about 20 days. After 12 months, the uncorrected visual acuity was 0.6-1.2, ≥ 0.6 in all eyes, 1.0 in 26 eyes (58%) and reached or exceeded the preoperative best corrected visual acuity in 35 eyes (78%). After surgery, the spherical degree was decreased from -2.5 m-1 to 0.5 m-1, and the cylinder degree was reduced from -3.85 m-1 to -0.53 m-1. High intraocular pressure occurred in 12 eyes, and 0.5-level corneal haze formed in 5 eyes. The results demonstrate that the excimer laser epithelial keratomileusis is safe and effective for treatment of refractive errors after cataract extraction and intraocular lens implantation.

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Key words: Lenses, Intraocular, Refractive Errors, Cataract Extraction

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