Non-living versus living-relative donor kidney transplantation: difference in perioperative blood transfusion

doi:10.3969/j.issn.2095-4344.2015.02.018

Abstract

Abstract:

BACKGROUND: Uremia patients have different degree of anemia before kidney transplantation, preoperative, and perioperative anemia is harmful to intraoperative and postoperative recovery of the organism and renal function.
OBJECTIVE: To observe the effects of perioperative anemia degree and total blood transfusion on non-living and living-relative donor kidney transplantation, and to summarize the perioperative drug treatment for anemia and perioperative principles of blood transfusion.
METHODS: A retrospective study was done in 115 cases of non-living donor kidney transplantation (test group) and 92 cases of living-relative donor kidney transplantation (control group) from January 2012 to December 2013. Degree of anemia, total perioperative blood transfusion, electrolyte change within 12 hours of blood transfusion, and adverse events after blood transfusion were recorded and analyzed.
RESULTS AND CONCLUSION: The incidence of anemia had no significant difference between the two groups (P > 0.05). Compared with the control group, the intraoperative and postoperative blood transfusion rate was higher in the test group (P < 0.05), and the preoperative red blood cell level, hemoglobin level, hematokrit, average hemoglobin level, average concentration of hemoglobin, and average amount of blood transfusions were significantly lower in the test group (P < 0.05). Fever (5.5%) was the main adverse event during the transfusion in the two groups, and there was no severe severe allergic reaction and electrolyte acid-base disturbance. These findings suggest that the perioperative degree of anemia is higher in patients undergoing non-living donor kidney transplantation and those undergoing living-relative donor kidney transplantation; preoperative drug treatment for anemia is crucial for correcting anemia status; intraoperative and/or postoperative blood transfusion treatment should be in strict accordance with the principles of perioperative blood transfusion.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

全文链接：

Key words: Kidney Transplantation, Anemia, Living Donors, Transplants

CLC Number:

R318

Zhang Li, Feng Gui-wen, Shang Wen-jun, Wang Zhi-gang, Zhang Bo-wei, Kang Yi-qing, Yang He-cai. Non-living versus living-relative donor kidney transplantation: difference in perioperative blood transfusion[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(2): 257-261.

Figures/Tables 2

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