Comparison of perioperative blood loss in the same patient undergoing staged joint replacement

doi:10.3969/j.issn.2095-4344.2014.48.005

Abstract

Abstract:

BACKGROUND: Perioperative blood loss is a common problem after orthopedic joint arthroplasty, however, anemia resulting from hidden blood loss has a strong impact on postoperative functional recovery. The related mechanism is still uncertain, numerous factors are complex, and the relevance is not clear.
OBJECTIVE: To observe the changes in perioperative blood loss in staged bilateral joint replacement patients, to avoid the influence of the difference among patients on hidden blood loss, and to discuss the relationship between hidden blood loss and related factors.
METHODS: A total of 19 patients, who received arthroplasty because of different diseases at different periods in Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA, were enrolled in this study.
Perioperative blood loss was analyzed in the same patient after staged bilateral joint replacement, including the correlation among dominant blood loss, hidden blood loss, staged surgery interval, disease type, kinds of surgery, length of operation, anticoagulant, regular blood detection after replacement and C-reactive protein.
RESULTS AND CONCLUSION: Preoperative values of hemoglobin and hematocrit in 19 patients were in the normal range, and no significant difference was detectable. By means of statistical analysis, significant difference on dominant blood loss was detected in staged surgery (P < 0.05). Correlation between many variables was analyzed using rank correlation and multiple regression analysis. There was significant correlation between staged surgery interval and dominant blood loss (P < 0.05). No obvious correlation was found between replacement type, anticoagulant and dominant blood loss, hidden blood loss. Severe dominant blood loss and hidden blood loss after replacement were significantly correlated with preoperative and postoperative C-reactive protein levels (P < 0.05), but not associated with length of stay. Above data suggested that severe hidden blood loss existed after replacement, which was associated with the individual, but not directly correlated with other external variables. If we make a comparative study in the large sample and same type of patients by retrospective or prospective methods, it will make a contribution to exploring the mechanism of hidden blood loss.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

全文链接：

Key words: arthroplasty, replacement, hip, arthroplasty, replacement, knee, blood loss, surgical, factor analysis, statistical

CLC Number:

R318

Yuan Lei, Bao Ni-rong, Zhao Jian-ning. Comparison of perioperative blood loss in the same patient undergoing staged joint replacement[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(48): 7732-7738.

Figures/Tables 1

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