Chinese Journal of Tissue Engineering Research

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The treatment of active hip and knee tuberculosis: One-stage arthroplasty feasible or not?

Pang Bo-tao, Cao Li   

  1. Department of Orthopedics, the First Affiliated Hospital of Xinjiang Medical University, Urumqi  830054, Xinjiang Uygur Autonomous Region, China
  • Received:2013-01-15 Revised:2013-03-09 Online:2013-06-25 Published:2013-06-25
  • Contact: Cao Li, Chief physician, Department of Orthopedics, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • About author:Pang Bo-tao★, Master, Department of Orthopedics, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China pangbotao@126.com

Abstract:

BACKGROUND: Efficacy of one-stage arthroplasty for patients with active hip and knee tuberculosis is significant, but whether the presence of prosthesis will increase the uberculosis recurrence risk is still the focus of debate.
OBJECTIVE: To review the basic and clinical research progress of one-stage arthroplasty for patients with active hip and knee tuberculosis.
METHODS: A computer-based online search of CNKI database, VIP database, Wanfang database and PubMed database between January 1985 and October 2012 was performed by the first author to search related articles with the key words of “hip tuberculosis, knee tuberculosis, mycobacterium tuberculosis, prosthesis, arthroplasty, replacement” in English or Chinese. A total of 258 literatures were primarily selected. According to the inclusion and exclusion criteria, finally 55 articles were included for review.
RESULTS AND CONCLUSION: One-stage arthroplasty is an effective method for the patients with active hip and knee tuberculosis. The presence of prosthesis will not affect the anti-tuberculosis drugs to kill mycobacterium tuberculosis; meanwhile, the large amount of molecular biology researches also provides a solid theoretical foundation for clinical treatment. With the deepening of research and surgeon experience accumulating, one-stage arthroplasty for the patients with active hip and knee tuberculosis will increasingly common.

Key words: bone and joint implants, bone and joint implant review, one-stage, prosthesis, arthroplasty, replacement, active, hip tuberculosis, knee tuberculosis

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