Chinese Journal of Tissue Engineering Research ›› 2020, Vol. 24 ›› Issue (4): 538-543.doi: 10.3969/j.issn.2095-4344.1925

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Factors affecting the clinical success rate of miniscrew implants for orthodontic treatment

Wu Yeke1, Gao Ranran2, Zuo Yuling1, Yu Jianfeng1, Zhao Lixing3, Nie Wenhan1, Zheng Tao4, Ai Huangping4, Yan Hang4   

  1. 1Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China; 2Henan Provincial People's Hospital, Zhengzhou 450000, Henan Province, China; 3West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan Province, China; 4Clinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China
  • Received:2019-03-27 Revised:2019-04-03 Accepted:2019-06-01 Online:2020-02-08 Published:2019-12-30
  • Contact: Wu Yeke, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China
  • About author:Wu Yeke, MD, Attending physician, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China
  • Supported by:
    the National Natural Science Foundation of China, No. 81500818, 81574035 and 81873334

Abstract:

BACKGROUND: During the orthodontic treatment, the results of related reports on potential risk factors affecting the clinical success rate of miniscrew implants are inconsistent. The influential factors that clinicians concern are not all included in this study, and the conclusions from animal experiments are difficult to apply to clinical practice directly. Therefore, what factors affect the clinical success rate of miniscrew implants need further thorough and systematic research.

OBJECTIVE: To investigate the factors that influence the clinical success rate of miniscrew implants used as orthodontic anchorage.

METHODS: A total of 114 patients with oral implants, including 42 males and 72 females, aged (19.26±9.19) years were included in this study. A total of 253 miniscrew implants were implanted as orthodontic anchorage. The following influential factors were included: gender, age, vertical skeletal facial pattern, implant site, implant arch, soft tissue type at the implant site, oral hygiene status, diameter and length of the miniscrew implants, implantation method, implantation angle, stress loading timing and intensity, and clinical use. Logistic regression analysis was used to study the correlation between success rate and all variables. Analysis of variance was used to test the effect of each variable on clinical success rate. This trial protocol was approved by the Medical Ethics Committee of Sichuan University.

RESULTS AND CONCLUSION: Among 253 successful miniscrew implants, the overall success rate was 88.54% with an average loading period of 9.5 months. The average loading period of the 29 failed miniscrew implants was 2.3 months. The chi-square test, Fisher exact test and Logistic regression revealed that age, oral hygiene, vertical skeletal facial pattern, and implant site were significantly correlated with clinical success rate (P < 0.05). However, gender, sagittal bone facial patter, implant arch, soft tissue type at implant site, diameter and length of miniscrew implant, implantation method, implantation angle, stress loading timing and strength, and clinical use were not significantly correlated to clinical use (P > 0.05). These results suggest that to minimize the failure of miniscrew implants, proper oral hygiene instruction and effective supervision should be given to patients, in particular to those young (< 12 years) high mandibular plane patients. 

Key words: miniscrew implants, clinical success, multivariate regression analysis, orthodontic anchorage, influential factor, implanting success rate, logistic regression analysis

CLC Number: