Application of three-dimensional printed antibiotic bone cement spacer in infected hip after hip arthroplasty for senile and infirm patients

doi:10.3969/j.issn.2095-4344.0191

Abstract

Abstract:

BACKGROUND: Infection after hip arthroplasty was a catastrophic complication for the senile and infirm patients. It was difficult for such patients to effectively control infection and retain certain hip function.

OBJECTIVE: To investigate the method and effect of three-dimensional (3D) printed antibiotic bone cement spacer as the terminal treatment of infection after hip arthroplasty for the senile and infirm patients.

METHODS: Between January 2014 and December 2016, the 3D printed antibiotic bone cement spacer of femoral head was used as the terminal treatment for four senile and infirm patients with artificial joint infection after hip arthroplasty. The wound healing, hip X-ray examination, infection indicators, Harris score, Visual Analogue Scale score were assessed postoperatively.

RESULTS AND CONCLUSION: (1) All patients were followed up for 8-35 months. In the four cases, wound healing without residual fistula was seen at postoperative 2 weeks. No revisions were performed at the last follow-up in four patients. Among them, one patient died of uremia-induced multiple organ failure at postoperative 9 months. (2) The infections were effectively controlled and the functions of hip were mostly retained after treatments by the 3D printed antibiotic bone cement spacer of femoral head. (3) Visual Analogue Scale score decreased from preoperatively (8.0±1.5) points to the last follow-up (2.0±1.4) points (P < 0.05). Harris score increased from preoperatively (41.6±4.2) points to the last follow-up (75.8±6.3) points (P < 0.05). (4) These findings conclude that 3D printed antibiotic bone cement spacer of femoral head can be used for effectively controlling hip infection and retaining most function of hip, for the senile and infirm patients with joint infection after hip arthroplasty. It can also be used as the ultimate treatment.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Arthroplasty, Replacement, Hip, Infection, Wound Healing, Tissue Engineering

CLC Number:

R318

Li Yuan-hui, Zeng Mian-dong, Yin De-long, Hu Han-sheng, Yu Sheng-hua, Wang Zhao . Application of three-dimensional printed antibiotic bone cement spacer in infected hip after hip arthroplasty for senile and infirm patients [J]. Chinese Journal of Tissue Engineering Research, 2018, 22(19): 3044-3048.

Figures/Tables 1

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