Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (16): 2981-2988.doi: 10.3969/j.issn.1673-8225.2012.16.030

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Biocompatibility and blood compatibility of artificial blood vessel materials  

Mao Zhi-gang1, Chen Zhao-hui2, Han Hong-guang2   

  1. 1Department of Cardiothoracic Surgery, the 463 Hospital of Chinese PLA, Shenyang 110042, Liaoning Province, China; 2Department of Cardiovascular surgery, General Hospital of Shenyang Military Area Command,Shenyang  110016Liaoning Province, China
  • Received:2012-01-20 Revised:2012-03-30 Online:2012-04-15 Published:2012-04-15
  • Contact: Han Hong-guang, Doctor, Associate chief physician, Master’s supervisor, Department of Cardiovascular Surgery, General Hospital of Shenyang Military Area Command, Shenyang 110016, Liaoning Province, China hanxiyao@163.com
  • About author:Mao Zhi-gang☆, Doctor, Associate chief physician, Department of Cardiothoracic Surgery, the 463 Hospital of Chinese PLA, Shenyang 110042, Liaoning Province, China mzg-czh@sohu.com

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Abstract:

BACKGROUND: With the development of biomedical engineering and biological materials science, artificial blood vessels have been widely used. The artificial blood vessel materials are constantly updated, How to improve the patency of blood vessels and the compatibility of the artificial blood vessel materials is the focus of research in recent years.
OBJECTIVE: Using CNKI database literature search and the depth of analysis capabilities, to perform the multi-level analysis for the literature data trends of artificial blood vessel materials.
DESIGN: Bibliometric data analysis.
DATA RETRIEVAL: A search of related literature of artificial blood vessel materials was performed in CNKI database using the key words of “Artificial blood vessels” and ”Biomaterials”, during 2002-01 to 2011-12. Database analysis capabilities and Excel charting functions were used for literature analysis, through the form of text and charts, its distribution characteristics were described.
SELECTION CRITERIA: ①Basic research papers related to the artificial blood vessel materials. ②Papers related to the clinical application of artificial blood vessel materials. Exclusion criteria: ①Literature has nothing to do with the purpose of this review. ②Duplication of research literature. ③Journal's own information. ④Unpublished papers. ⑤The article need telephone follow up to analyze and manual searches. ⑥Yearbook.
MAIN OUTCOME MEASUREMENTS: In CNKI database, using academic journal articles published year, literature number, subject category, research institutions, source journals, literature citations, literature download frequency, associated literature, distribution of the author, distribution of the funds and major keywords to analysis. Regarding doctoral dissertation, the outstanding master’s degree papers, conference papers and patented technology to analyze.
RESULTS: The literature associated with academic journals in CNKI during 2002-2011, retrieved a total of 122 artificial blood vessel materials research literature. The number of papers was gradually increasing. Published the most in 2008, a total of 17. Journal of Clinical Rehabilitative Tissue engineering Research published literatures is 27, accounting for 22.1% of all literature. The artificial blood vessel materials science research funded mainly by the National Natural Science Foundation of China, a total of 30. The artificial blood vessel materials research mainly based on Polyurethane, to highlight materials science biocompatibility and hemocompatibility studies.
CONCLUSION: Through the bibliometric data analysis based on CNKI database of academic journal literature of the artificial blood vessel materials, to provide valuable reference for Chinese medical worker in artificial blood vessel materials science basic research and clinical practice, to further define the thinking of scientific research.

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