Abstract:

BACKGROUND: Fibrin glue is widely applied for blood oozing wounds in various surgeries.
OBJECTIVE: To apply absorbable fibrin glue and gelatin sponge in partial liver resection so as to analyse the operation time and postoperative hemostasis effect.
METHODS: Totally 42 patients undergoing partial liver resection were randomly divided into two groups: in the control group defects of liver tissue were folded after partial hepatectomy and hemostasis; in the experimental group, the wound was sprayed with fibrin glue to achieve hemostasis effect and the defect was filled with fibrin glue and gelatin sponge cutting into pieces to replace the conventional suture.
RESULTS AND CONCLUSION: Operation time, bleeding volume, drainage volume and duration of blood oozing in the experimental group were significantly lower than those in the control group (P < 0.05), while length of hospital stay and hospital costs had no difference between the two groups (P > 0.05). Combined application of fibrin glue and gelatin sponge in partial liver resection can effectively reduce the operation time and reduce postoperative hemorrhage without increasing patient’s cost and hospital stay.