Abstract:

BACKGROUND: In recent years, wound dressings made of different materials in various forms develop rapidly; composite application form, gel form and drug-membrane form are the current hot spots of research and application.
OBJECTIVE: To evaluate the experimental study and clinical application of different wound dressings.
METHODS: A computer-based online search of VIP database was performed for relevant articles published between January 2002 and October 2011, with the key words of “dressing”, “wound”, “experiment” and “application”. Randomized controlled studies relevant to dressings and wounds were included; repetitive studies and Meta analysis were excluded. The analysis was based on 22 documents.
RESULTS AND CONCLUSION: Nano-silver, povidone iodine, chitosan and Kangfuxin are main materials used for wound repair in experimental animals; the anti-infection effect and wound healing promotion are the maximum when the materials are composited with hollow activated carbon fibers and gelatin sponge respectively or made into in situ gel form or drug-membrane form. Chitosan, nano-silver, silver ion, pig collagen fibers, bio-optical elements, Algisite M Calcium Alginate, Allevyn and other materials in composite form or hydrogel form are used for wound repair in clinic; these forms will help their performance, and better promote the wound healing.