Abstract:

BACKGROUND: The volume regimens through different stages in renal transplantation. But which liquid treatment strategy is more reasonable and effective is still unclear.
OBJECTIVE: To compare three different volume regimens for kidney transplantation by observing the effect on hemodynamics and turnover.
METHODS: Retrospectively analysis was done in 255 patients undergoing homogeneity variant kidney transplantation. The patients were divided into three groups according to the type of the infusion liquid: Colloids (crystalloids+succinylated gelatin+red blood cells+albumin) group, crystalloids and red blood cells group and crystalloids group. Analysis indexes included general information, perioperative data and postoperative follow-up data.
RESULTS AND CONCLUSION: Although crystalloid infusion was contributed to the protection of renal function during renal transplantation, the effect of expansion was weak and the duration of expansion was short, as well as it was not conducive to maintain the stable hemodynamics, and easily led to electrolyte imbalance. The crystalloid infusion in renal transplantation should apply the equilibrium liquid mainly instead of normal saline. The combination of crystalloid and colloid infusion was conducive to stabilize the hemodynamics, but had no advantage for the protection of renal function. The equilibrium liquid was mainly used and red blood cells were infused when necessary. This volume regimen could maintain hemodynamics stable and homeostasis stable, and profit to turnover. It may be the best volume regimen for renal transplantation.