BACKGROUND: The key points of large area skin grafting are blocking wound surface, decreasing exudation and avoiding diff-healing wounds. A new wound surface dressing biomaterial can improve the achievement ratio of skin grafting.
OBJECTIVE: To study the curative effect of vacuum-sealing drainage (VSD) based on wound surface dressing biomaterials on large area skin grafting.
METHODS: Sixty patients with large area skin grafting were divided into three groups by their wishes: wound surface bio-dressing group, synthetic material group and routine pressure dressing group. Dressing group patients were covered by wound surface dressing biomaterials and synthetic materials after debridement and skin graft, and then biological semipermeable membrane was used to construct a vacuum device or routine pressure dressing directly. The coverage of skin grafting was calculated at one week after skin grafting.
RESULTS AND CONCLUSION: The coverage of skin grafting was improved by using VSD. The coverage of skin grafting in the wound surface dressing biomaterial group was higher than that of the synthetic material group (P < 0.05). Compared with the routine pressure dressing group the coverage of skin grafting was significantly increased in the other two groups. New wound surface dressing biomaterials can improve the curative effect of VSD.