Abstract:

ACKGROUND: Stent implantation is an effective way to treat coronary heart disease.
OBJECTIVE: To study the effects of different cardiovascular stent materials on vascular restenosis and endothelin content in elderly patients with coronary heart disease.
METHODS: The first author searched VIP databases for articles published 1995-01/2011-06 using the keywords of cardiovascular stents, elderly coronary heart disease, endothelin, vascular restenosis”.
RESULTS AND CONCLUSION: Diffuse coronary vascular disease, vascular wall damage, thrombosis, inflammatory factors and cytokines are more seen in elderly patients than young and middle-aged patients receiving simple balloon angioplasty. Postoperative long- and middle-term vascular restenosis rate is also higher in young and middle-aged patients. Bare-metal stents can reduce the incidence of vascular restenosis and thrombosis and the production of various growth factors and cytokines as compared with simple balloon angioplasty. Drug stents are effective to inhibit vascular recoil and negative remodeling, reduce the incidence of long- and middle-term restenosis, decrease the occurrence of complications and improve the quality of life of elderly patients with coronary heart disease.