Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (1): 139-142.doi: 10.3969/j.issn.1673-8225.2012.01.030

Previous Articles     Next Articles

Effect of bone marrow msenchymal stem cells on the treatment of glioma   

Cao Pei-chao, Wang Jian-jiao, Zheng Yong-ri   

  1. Ward Two, Department of Neurosurgery, Second Affiliated Hospital of Harbin Medical University, Harbin  150086, Heilongjiang Province, China
  • Received:2011-11-01 Revised:2011-11-26 Online:2012-01-01 Published:2012-01-01
  • Contact: Zheng Yong-ri, Doctor, Chief physician, Professor, Master’s supervisor, Ward Two, Department of Neurosurgery, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, Heilongjiang Province, China zyr63@medmail.com
  • About author:Cao Pei-chao★, Studying for master’s degree, Ward Two, Department of Neurosurgery, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, Heilongjiang Province, China chaochao2004118@sina.com
  • Supported by:

    Science Foundation of Heilongjiang Education Bureau, No. 11541203*

PDF

316

Abstract:

BACKGROUND: Bone marrow msenchymal stem cells (BMSCs) have become the ideal cell vector for the treatment of glioma.
OBJECTIVE: To understand the research process and related mechanism of BMSCs in glioma therapy research.
METHODS: We searched Pubmed database (1990/2011-01) with the key words “bone marrow mesenchymal stem cells, mesenchymal stem cells, Multipotent stem cells,Treatment of glioma,Gene therapy”. The basic, perspective and clinical research articles that related to the biological characteristics of the BMSCs and the effect of the BMSCs on the treatment of glioma was included. The duplicate articles were excluded.
RESULTS AND CONCLUSION: More than 109 articles were screened out by computer according to inclusive and exclusive criteria, 34 documents of which were involved for analysis. Articles were described the biological characteristics of BMSCs, compared the animal experiments and the clinical research of BMSCs transplantation for treatment of glioma, and it confirmed that BMSCs as vectors for gene therapy of glioma had good development prospects in glioma treatment.

CLC Number: