Abstract:

BACKGROUND: High levels of fast-paced sports game is likely to cause muscle damage which is hopeful to repair because of muscle tissue engineering.
OBJECTICE: To review the research status of muscle tissue engineering for tissue engineering exercise-induced muscle injury studies provide a theoretical basis.
METHODS: The articles from PubMed database between January 1994 and December 2010 were retrieved by computer with the key words of “tissue engineering, anterior cruciate ligament repair, biological material scaffold, cytokines, seed cells.” Articles related to exercise-induced muscle damage and muscle tissue engineering were included. Meta-analysis an duplicate studies were excluded.
RESULTS AND CONCLUSION: A total of 15 literatures were included. Current researches projects in four areas include rebuilding muscle tissue, extracellular matrix composite materials, muscle tissue engineering seed cells sources, matrix scaffold. Current researches show that exercise-induced muscle tissue engineering for the treatment of muscle injuries has a good prospect. However, in practice applications, muscle tissue-engineered seed cells selection, scaffold construction, extracellular matrix composite materials research and organizational compatibility are the still the difficult problems of muscle tissue engineering.