Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (50): 9473-9476.doi: 10.3969/j.issn.1673-8225.2011.50.040

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Effects of creatine supplementation on skeletal muscle energy metabolism in old adults

Jiang Yu-xing1, Wang Xu-lou2, Gao Qian-jin2   

  1. 1Department of Physical Education, Hebei Normal University, Shijiazhuang 050024, Hebei Province, China
    2Department of Physical Education, Shijiazhuang University, Shijiazhuang 050035, Hebei Province, China
  • Received:2011-05-16 Revised:2011-05-27 Online:2011-12-10 Published:2011-12-10
  • About author:Jiang Yu-xing★, Master, Department of Physical Education, Hebei Normal University, Shijiazhuang 050024, Hebei Province, China gtbxjwb@mail.hebtu.edu.cn

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Abstract:

BACKGROUND: Research shows that creatine supplementation is a safe and effective method to diminish age-related declines in muscle mass and strength.
OBJECTIVE: To summarize studies about the effects of creatine supplementation on skeletal muscle energy metabolism, exercise capacity and life quality in old adults.
METHODS: An online search of PubMed database and CNKI was performed using key words of “creatine; old adults; skeletal muscle; phosphocreatine; strength” for articles published before March 2011, both in English and Chinese. Papers about effects of creatine supplementation on skeletal muscle energy metabolism and exercise capacity in old adults were included, and repetitive researches were excluded.
RESULTS AND CONCLUSION: A total of 72 documents were retrieved, and 38 articles were retained after depleting unrelated and repetitive ones. The recent researches concerning the effects of creatine supplementation on intramuscular energy metabolism, skeletal muscle morphology and life quality in old adults were summarized. Creatine can increase muscle strength, induce muscle hypertrophy and improve the exercise capacity of old adults. Creatine supplementation is a safe, inexpensive and effective nutritional intervention. It can slow the muscle wasting rate associated with aging, especially when consumed in conjunction with resistance training.

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