Abstract:

BACKGROUND: The receptor regulates and switches signal and starts intracellular signal transduction, which causes target cells to produce biological effects. Receptor regulation is an important regulation mode for organism to motor adaptation.
OBJECTIVE: To summarize the effects of motor on receptor, the adaptative change of receptor, and signal transduction rule of motor receptor cells. 
METHODS: A computer-based retrieval was performed by the first author to search manuscripts in the CNKI (2000/2010) and Medline database (2000/2010) with the key word “receptor regulation, exercise, adaption”. A total of 137 manuscripts were included. According to inclusion and exclusion criteria, totally 37 manuscripts were included in the final analysis. The included manuscripts were summarized in terms of receptor concept, receptor classification and function, receptor function and regulation, the effects of motor on receptor, and adaptative change of receptor in exercise, as well as the regulation mechanism of receptor.
RESULTS AND CONCLUSION: Exercise could up regulate leptin receptor and insulin receptor, leading to adaptative change of androgen and insulin secretion. Proper exercise increased androgen receptor binding capacity and receptor numbers. Long-term high-intensity or exhaustive exercise decreased androgen receptor binding capacity and receptor numbers, which protect cells from excessive or long-term stimulation-caused physiological dysfunction. Acute stress reduced glucocorticoid receptor level in each tissue organs, and showed important significance for preventing from substance metabolism and energy metabolism disturbance and maintaining homoeostasis.