Abstract:

BACKGROUND: High intensity of exercise can lead to injury to fine structure of skeletal muscle tissue, and the activation, proliferation and differentiation of skeletal muscle satellite cells are closely related to muscle tissue injury.
OBJECTIVE: Based on the thinking that training can cause muscle structural damage and repair is needed, this study proposed a dependent relationship between repair of skeletal muscle structure and skeletal muscle satellite cells.
METHODS: A computer-based retrieval was performed by the first author to search manuscripts in CNKI and Medline database published between 2000 and 2010 with the key words “skeletal muscle satellite cells, growth factor, exercise, and skeletal muscle ultrastructure” in English and Chinese languages. A total of 97 manuscripts were retrieved. Following inclusion and exclusion criteria, 23 manuscripts were included in the final analysis. The mechanism underlying skeletal tissue repair and skeletal muscle satellite cell activation was summarized, and the relationship between these two was analyzed.
RESULTS AND CONCLUSION: High intensity of exercise can result in injury to skeletal muscle tissue, satellite cells are the key to skeletal muscle repair and the growth factors of satellite cells are also related to exercise methods. At present, the relationship between skeletal muscle satellite cells growth factors and exercise lacks of sufficient recognition and research.