Abstract:

BACKGROUND: Polyetgeretherketone has good biocompatibility, but its modulus and mechanical strength characteristics drop badly upon glass-transition temperature, so as to fail to provide a steady condition for bone growth.  
OBJECTIVE: To observe the biocompatibility and biomechanics of short carbon fiber reinforced polyetgeretherketone as hip prosthesis by animal experiment.
METHODS: The biocompatibility in vitro was measured by MTT, hemolysis test, acute toxicity experiment and pyrogen experiment; SCF/PEEK composite plates were implanted into the rabbits, and the formation of fibrous capsules and general tissues conditions around the plates were observed under the optical microscope; The stress tests were carried on the WE-SA universal testing machine.
RESULTS AND CONCLUSION: The relative survival rate was > 75%, the hemolysis rate < 5%, indicating a good blood compatibility. There was no evident difference between the two groups. As the time goes on, the relation between the implanted-plates and capsules was more and more close, and inflammatory cells became gradually less.