Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (33): 6115-6117.doi: 10.3969/j.issn.1673-8225.2011.33.009

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Balneotherapy combined with electrical stimulation for treatment of disuse osteoporosis

Zhao Ting-gang   

  1. Department of Physical Education, Yibin University, Yibin   644000, Sichuan Province, China
  • Received:2011-05-10 Revised:2011-06-30 Online:2011-08-13 Published:2011-08-13
  • About author:Zhao Ting-gang, Lecturer, Department of Physical Education, Yibin University, Yibin 644000, Sichuan Province, China ztgls100@163.com

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Abstract:

BACKGROUND: Both electrical stimulation and balneotherapy exhibit therapeutic effects on disuse osteoporosis. The combined application of these two methods has been rarely reported.
OBJECTIVE: To investigate the effects of electrical stimulation combined with balneotherapy on biomechanics of rat models of disuse osteoporosis.
METHODS: Sprague-Dawley rat models of disuse osteoporosis were developed by resection of sciatic nerve and femoral nerve. After wound healing, rats were interfered for 8 weeks with electrical stimulation, balneotherapy or their combination. Rat body weight and femoral biomechanics were investigated.
RESULTS AND CONCLUSION: After denervation, body mass of rats with disuse osteoporosis was greatly increased, the femur exhibited obvious abnormality in material and structural mechanics. After electrical stimulation and (or) balneotherapy, body mass of rats with disuse osteoporosis was decreased, and the material and structural mechanics were improved. In particular after electrical stimulation combined with balneotherapy, the maximum load, breaking load, elastic modulus, and ultimate strength of the femur of rats with disuse osteoporosis were obviously improved.

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