Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (14): 2629-2632.doi: 10.3969/j.issn.1673-8225.2011.14.035

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Research progress in tumor stem cells

Hou Ping, Li Jian-ping   

  1. Institute of Transfusion Medicine, Liaoning Blood Center, Shenyang  110044, Liaoning Province, China
  • Received:2010-11-17 Revised:2011-01-20 Online:2011-04-02 Published:2013-11-02
  • Contact: Li Jian-ping, Chief physician, Institute of Transfusion Medicine, Liaoning Blood Center, Shenyang 110044, Liaoning Province, China ljp_63@yahoo.com
  • About author:Hou Ping★, Master, Attending physician, Institute of Transfusion Medicine, Liaoning Blood Center, Shenyang 110044, Liaoning Province, China houping77@163.com

Abstract:

BACKGROUND: Tumor stem cells have a strong proliferation and differentiation, but different from normal stem cells.These stem cells also has developed into tumor, so they are widely concerned by scholars.
OBJECTIVE: To review the characteristic of tumor stem cells and the relationship with stem cells and tumor, and clinical significance.
METHODS: A computer-based online search of PubMed database, CNKI database, Wanfang database for articles of tumor stem cells was performed with the key words of “tumor stem cell” in Chinese and English, respectively. A total of 89 literatures were retrieved, and 30 documents of which were included.
RESULTS AND CONCLUSION: At present, tumor stem cell is still in the stage of basic research in China, while tumor stem cell has made some progress on experimental research and clinical application at abroad. It generally believed that tumor stem cells are existed in tumor tissue. Tumor stem cells play an important role in development and treatment of tumor, tumor stem cells for the treatment of tumor are also very optimistic about the prospects of clinical application, but the characteristics of tumor stem cells and relation with adult stem cells are still in the preliminary research stage.

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