Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (11): 2059-2063.doi: 10.3969/j.issn.1673-8225.2011.11.040

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Effects of environmental hormone on embryonic development

Hu Meng-sang, Chen Yi-fei, Xu Ying   

  1. Medical College of Jiaxing University, Jiaxing  314001, Zhejiang Province, China
  • Received:2010-10-10 Revised:2010-12-02 Online:2011-03-12 Published:2011-03-12
  • Contact: Xu Ying, Doctor, Associate professor, Medical College of Jiaxing University, Jiaxing 314001, Zhejiang Province, China Xuyingmrd@yahoo. com
  • About author:Hu Meng-sang, Medical College of Jiaxing University, Jiaxing 314001, Zhejiang Province, China 418828171@qq.com
  • Supported by:

    the Experimental Animal Platform Plan of Zhejiang Province, No. 2008F80025*; the Science and Technology Program of Jiaxing City, No. 2010AY1098*; the Science and Technology Innovation Plan for University Students of Zhejiang Province, No. 851910104* 

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Abstract:

BACKGROUND: Many studies have shown that the increasing occurrence of reproductive abnormalities in wild life may be associated with exposure to environmental hormone. With the pollution of the environment, effects of environmental hormone on embryonic development have been paid more and more attention.
OBJECTIVE: To review the effects and possible mechanism of various environmental hormone on the process of embryo implantation, embryonic development during preimplantation and the development of embryonic reproductive system.
METHODS: CNKI database and Pubmed database were searched using key words of “environmental hormone and diethylstilbestrol, mifepristone, methoxychlor, bisphenol A, tetrachlorodibenzo-p-dioxin, embryonic development, early embryonic development”, for papers addressing the effects of environmental hormone on embryonic development.
RESULTS AND CONCLUSION: Totally 45 articles were adapted. Common environmental hormones widely spread in daily life in a great variety. Different environmental hormones have synergistic reaction. The mechanism exploration is at the step stage. It is necessary to control production source of environmental hormones and reduce anthropogenic discharge to decline the effect of environmental hormones on human healthy. 

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