Abstract:

BACKGROUND: The morbidity of pterygium was higher in the north of China. When we used the traditional operation to cut off pterygium, the cornea may shape the astigmatism and recrudesce was higher. Patient may need second treatment or more.
OBJECTIVE: To observe the curative effect of human fresh amnion transplantation in treating pterygium.
METHODS: A total of 48 cases with pterygium (58 eyes) were randomly divided into the transplantation and traditional operation groups, which were underwent fresh amnion transplantation or simple pterygium excision under a microscope. All cases were followed up for 6-12 months. The recurrence of pterygium and repair of cornea were observed.
RESULTS AND CONCLUSION: At the last followed-up visit, 27 eyes were healed and 2 eyes were recurrence in the transplantation group, the recurrence rate was 6%. 25 eyes were healed and 4 eyes were recurrence in the traditional operation group, the recurrence rate was 13%. There were significance differences between two groups (P < 0.05). Transplanting of fresh amnion in the pterygium cutting operation can effectively reduce the recurrence of pterygium, but its long-term effect needs further verified.