Abstract:

BACKGROUND: Due to interrupt of neural pathway after spinal cord injury, bladder loss normal control, and lead to urinary retention or renal damage. The reconstruction of bladder function has been the difficulty of the nervous urology. Neuroprostheses transplantation is considered an effective method to reconstruct functions.
OBJECTIVE: To investigate the latest development of neuroprostheses for the treatment of neurogenic bladder after spinal cord injury.
METHODS: CNKI and springer database were searched by computer for papers related to neuroprostheses for the treatment of neurogenic bladder after spinal cord injury published from January 1988 to December 2009. In the title and summary, “neuroprostheses, implantion, treat, neurogenic bladder, electrical stimulation” were served as key words. These articles were linked to neuroprostheses transplantation to treat neurogenic bladder and published in the authoritative journal were selected. Totally 44 articles were included according to the inclusive criteria. 
RESULTS AND CONCLUSION: At present, there is no significant progress in spinal cord regeneration. Neurolprostheses has become the primary means to reconstruction nerve function. There are two neuroprostheses to treat neurogenic bladder in clinical: one is Finetech-Brindley bladder system, the other is InterStim-Therapy bladder system. In recent years, the launch of four new technology bring revolutionary changes to neurogenic bladder treatment, including: anoda blocking technique, conditional electrical stimulation, injectable neuroprostheses and electrical stimulate the pudendal nerve branches.