Abstract:

BACKGROUND: Surgical aortic valve replacement is the primary treatment of aortic stenosis. However, percutaneous aortic valve replacement is preferred for patients with old age, multiple co-morbidities and high operative risks.
OBJECTIVE: To summarize the application progress of pervutaneous aortic valve replacement in the treatment of cardiovascular diseases.
METHODS: The databases of PubMed (http://www.ncbi.nlm.nih.gov/PubMed) and Wanfang (http://www.wanfangdata.com.cn) were retrieved by the first author using key words of “aortic stenosis, percutaneous aortic valve replacement and valve stent”. Repetitive studies were excluded. Totally 63 documents were initially searched, and 25 literatures were included in the further analysis.
RESULTS AND CONCLUSION: Since the first percutaneous aortic valve replacement in 2002, valve stents and procedural approaches have got an unprecedented development. However, there are many defects in percutaneous aortic valve replacement, such as valve displacement or perivalvular leakage resulted from poor fixation of valve matrix, thrombosis, aortic insufficiency, and low popular rate. With the improvement of surgical methods and valve development, percutaneous aortic valve replacement would be a good method for patients with aortic stenosis.