Abstract:

BACKGROUND: Pulmonary infection is the common complication and main cause of death after renal transplantation.
OBJECTIVE: To comprehensively analyze the characteristics, clinical manifestations, diagnosis and treatment of pulmonary infection after renal transplantation.
METHODS: A computer-based database online search of PubMed Database was undertaken to identify articles of the characteristics, clinical diagnosis and treatment of pulmonary infection after renal transplantation published in English from 1997 to 2010 with key words of "kidney transplantation, pulmonary infection". Wanfang Database was searched for the same articles published from 2001 to 2010 in Chinese with the key words of “kidney transplantation, pulmonary infection”. The repetitive study was excluded. Finally, 21 articles were included according to inclusion criteria.
RESULTS AND CONCLUSION: The clinical symptoms of pulmonary infection in renal transplantation are not identical to that of the common man. The symptoms are not typical. They can be detected by various means, and need to adjust immunosuppressant and regulatory treatment. Pulmonary infection should be prevented and treated with early diagnosis and treatment, drug combination, sufficient dose and full course of treatment. The dose of immunosuppressive drug should be adjusted according to the patients’ body condition and at various periods.