Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (44): 8273-8276.doi: 10.3969/j.issn.1673-8225.2010.44.026

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Superiority analysis of 69 living-related renal transplant recipients in a single center within 2 years

Wang Qiang1, Li Xiao-li2, Cai Ming1, Shi Bing-yi1, Qian Ye-yong1, Li Zhou-li1, Xu Liang1   

  1. 1 First Department of Urology, 2 Department of Cadre Ward, the 309 Hospital of Chinese PLA, Beijing  100091, China
  • Online:2010-10-29 Published:2010-10-29
  • Contact: Cai Ming, Doctor, Chief physician, Master’s supervisor, First Department of Urology, the 309 Hospital of Chinese PLA, Beijing 100091, China caiming@medmail.com.cn
  • About author:Wang Qiang★, Master, Associate chief physician, First Department of Urology, the 309 Hospital of Chinese PLA, Beijing 100091, China wq301135@yahoo.com.cn

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Abstract:

BACKGROUND: Living-related renal transplantation is still at the beginning stage in China, and the large sample clinical data are insufficient. Thus, Boao consensus was achieved for the normalization of living-related renal transplantation.
OBJECTIVE: To retrospectively analyze the clinical experience of living-related renal transplant recipients in a single center.
METHODS: Totally 69 living-related renal transplant recipients at the Organ Transplantation Center, 309 Hospital of Chinese PLA, between January 2006 and March 2008, were retrospectively analyzed, 39 cases were parents donation to the children; 1 was children donation to parents; 19 were sibling donation; 7 cases were three generations of collateral serum; 3 cases of donation happened between husband and wife. 66 cases had the same ABO blood group, 3 cases of which were compatible; there are 5 cases with HLA mismatch, 31 cases of mismatch in 2 points, 32 in one point and 1 in 4 points; 66 persons were admitted for the left kidney and 3 persons for right kidney; 69 cases were all admitted for kidney through open surgery. Rejection was prevented by the use of cyclosporine / Prograf+ Mycophenolate Mofetil / azathioprine + Prednisone.
RESULTS AND CONCLUSION: Of 69 living-related renal transplant recipients, none had renal failure after transplantation, and the 1-year survival rate was 100%. The average warm ischemia time was (3.56±1.42) minutes and the average cold ischemia time was (45.12±25.34) minutes: the time when postoperative renal function returned to normal level was (5.6±7.0) days. 9 cases showed rejection at 3 months after surgery, 2 cases showed pulmonary infection, 3 cases had delayed graft function, 1 case got renal artery stenosis, 2 cases with bone marrow suppression, 1with brain root block, and 1 case with urinary fistula. With the rigorous and comprehensive assessment of living renal transplantation, living kidney transplantation has advantages of few complications, fast recovery and low incidence of rejection, is one of the main ways uremic patients take home self-help.

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