Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (44): 8220-8224.doi: 10.3969/j.issn.1673-8225.2010.44.013

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Effects of cardiothoracic ratio following cardiac valve replacement: A Meta-analysis

Hou Yuan-yuan, Zhou Ping   

  1. School of Biomedical Engineering, Capital Medical University, Beijing  100069, China
  • Online:2010-10-29 Published:2010-10-29
  • Contact: Zhou Ping, Master, Associate professor, School of Biomedical Engineering, Capital Medical University, Beijing 100069, China eduhelp@163.com
  • About author:Hou Yuan-yuan★, Studying for master’s degree, School of Biomedical Engineering, Capital Medical University, Beijing 100069, China hyy200333@163.com

Abstract:

BACKGROUND: Because of the high risk and high cost of cardiac valve replacement, it is necessary to perform pre-operative assessment for a successful operation. It can accurately measure cardiothoracic ratio (CTR) and clearly show the structure and function of the heart from the chest X-ray. If the CTR ≥ 0.7, it means severe cardiac valve disease, and operation risk is higher.
OBJECTIVE: To investigate the effects of CTR on mortality rate and complications after cardiac valve replacement according to Meta analysis, and to calculate the CTR mean of four heart function using the data mining method.
METHODS: The CNKI database, Wanfang database, and Vip database were retrieved. The literatures addressing cardiac valve replacement in China were collected from the relevant date. Meta analysis was carried out based on two groups of CTR > 0.7 and CTR < 0.7. The differences in evaluation were expressed by odds ratio (OR) and 95% confidence interval (CI). RevMan 4.2 software was used for statistical analysis. The preoperative CTR mean of four cardiac functions was calculated by the data mining method.
RESULTS AND CONCLUSION: A total of 8 articles about mortality rate, and 9 articles about complications were included. Result of meta- analysis showed that CTR had significant effects on postoperative mortality rate and complications in the two groups of CTR. Eight sets of data in postoperative mortality in the 8 literature had the same results after the heterogeneity inspection (P=0.19); however, 6 sets of data in postoperative complications in the 9 literature had the inconsistent results after the heterogeneity test (P < 0.000 1). The CTR mean of preoperative cardiac function in II, III, IV patients was 0.555 9, 0.669 0, and 0.671 2 respectively. It is indicated that if preoperative CTR > 0.7 in patients, the early mortality rate and complications is higher after the cardiac valve replacement. The CTR can be used as one of the preoperative risk assessment indexes for cardiac valve replacement. It is valuable to statistics CTR according to preoperative heart level.

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