Abstract:

BACKGROUND: The pathological changes of chronic transplant kidney function insufficiency can influence directly the blood flow perfusion of renal glomerula. The blood flow perfusion of renal glomerula can be evaluated by monitoring microcirculation perfusion of renal graft cortex. When chronic renal glomerular filtration insufficiency occurred, it has important clinical value to real-time monitor pathological changes of microcirculation perfusion of renal graft cortex.
OBJECTIVE: To summarize pathological changes of microcirculation perfusion of renal graft cortex when chronic renal glomerular filtration insufficiency occurred by SonoVue ultrasound contrast imaging.
METHODS: Totally 32 patients received allogeneic kidney transplantation, including 21 males and 11 females, with aged 38-60 years. The post-operation times of all patients were above 6 months. The serum creatinine and urea nitrogen values of all patients were above normal. The microcirculation perfusion of renal graft cortex was monitored real-time by SonoVue ultrasound contrast imaging. The images were stored real-time and analyzed by review.
RESULTS AND CONCLUSION: All 32 patients were successfully examined with ultrasound contrast imaging. PT of all patients was above 25 ms, T of all patients was above 15 ms, the distribution of agent was not uniform. The results show that the pathological changes of microcirculation perfusion of renal graft cortex could be real-time monitor by SonoVue ultrasound contrast imaging when chronic renal glomerular filtration insufficiency occurred.