Abstract:

BACKGROUND: A large amount of clinical trials have demonstrated that the application of domestic rapamycin-eluted stent is safe and biocompatible in selective coronary artery interventional operation. However, its reliability and effectiveness remain controversial when applied on patients with acute myocardial infarction.
OBJECTIVE: To evaluate the therapeutic effect of rapamycin eluted stent via percutaneous coronary implantation on acute myocardial infarction.
METHODS: Emergency percutaneous coronary interventions were applied in 108 cases of acute myocardial infarction by the implantation of domestic rapamycin-eluted stent, all patients including 61 males and 47 females aged 37-81 years with a mean of (57.2±13.1) years received routine medication preoperatively and postoperatively. The improvement of TIMI blood flow of infarction-related artery was rating. Major cardiac events including the incidence of cardiac death, non-fatal myocardial infarction, target vessel revascularization was evaluated in 6-12 months of follow-up in outpatient department or by a call visiting.
RESULTS AND CONCLUSION: After stent implantation, the TIMI blood flow was graded as Ⅰ-Ⅱ in 6 cases (5.6%), as Ⅲ in 102 cases (94.4%). The achievement ratio of implantation is 100%, the clinical success ratio is 98.1%, the incidence of major adverse cardiac events is 1.87% and 3.74% at the sixth month and the twelfth month respectively. The rapamycin-eluted stent is safe and effective in the percutaneous coronary intervention of acute myocardial infarction patients.