Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (37): 6899-6903.doi: 10.3969/j.issn.1673-8225.2010.37.014

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Construction and evaluation of SD rat exercise training models under different work intensities

Zhou Wei1, Chen Li-jun2, Zhang Min2, Jin Qiu-yue2, Yao Li2   

  1. 1 Graduate Management Brigade, 2 Department of Biochemistry, Medical College of Chinese People’s Armed Police Force, Tianjin  300162, China
  • Online:2010-09-10 Published:2010-09-10
  • Contact: Chen Li-jun, Master, Professor, Department of Biochemistry, Medical College of Chinese People’s Armed Police Force, Tianjin 300162, China chenlijun67@eyou.com
  • About author:Zhou Wei★, Studying for master’s degree, Graduate Management Brigade, Medical College of Chinese People’s Armed Police Force, Tianjin 300162, China 1987715212@163.com
  • Supported by:

     the Key Item of Medical College of Chinese People’s Armed Police Force, No. WKH2009Z02*

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Abstract:

BACKGROUND: Currently, studies of energy metabolism changes in movement training focus on skeletal muscle mitocheondrial biogenesis, oxygen free radicals and other indexes. But studies regarding physical mechanisms of energy metabolism under different work intensities are few.
OBJECTIVE: To observe the energy metabolism changes of the SD rats via constructing motion models of aerobic exercise, anaerobic exercise and aerobic and anaerobic cross-training.
METHODS: Using treadmill running to establish the motion models. The aerobic exercise group was constructed by incremental exercise, and the anaerobic exercise group treated with high-speed interval training. Meanwhile, the normal control group was established. The body weights were weighted before and after exercise. The content of lactate, lactate dehydrogenase, creatinine, urea nitrogen, creatinekinase, pyruvatedehydrogenase (PK) and succinic dehydrogenase (SDH) in rat serum were determined after exercise. 
RESULTS AND CONCLUSION: The results showed that. Weight loss of rats in the anaerobic exercise group was markedly decreased (P < 0.05) and the content of lactate increased (P < 0.05). Content of SDH in rat serum from the anaerobic exercise group was smaller than that in the aerobic exercise group (P < 0.05). Serum lactate dehydrogenase of anaerobic exercise group and crossing-training group were also increased (P < 0.05). The contents of serum urea nitrogen in three exercise groups were extremely higher than that in the normal control group (P < 0.001). Serum creatinekinase and creatinine in the crossing-training group were significantly higher compared with other three groups (P < 0.01). The level of PK in rat serum from crossing-training group was also higher than that in the other groups (P < 0.05). The metabolic levels of rats in three exercise groups were consistent with the evaluation of aerobic exercise, anaerobic exercise, aerobic and anaerobic crossing-training metabolisms. Thus, the exercise training models were successfully constructed.

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