Abstract:

BACKGROUND: Infant liver transplantation is difficult, with high postoperative complications and difficult perioperative management. Domestic clinical experience in liver transplantation lacks due to short application and small case.
OBJECTIVE: To investigate the early complication of liver transplantation in infants and discuss the experiences in prevention and treatment methods.
METHODS: From September 2006 to January 2010, 14 infants underwent liver transplantation in First Central Hospital of Tianjin, aged 6 months to 2 years and 8 months, including 1iving related liver transplantation in 8 cases and split liver transplantation in 6 cases. Preoperative condition, operation patterns, perioperative treatment, postoperative general condition and complications were recorded.
RESULTS AND COCNLUSION: Of 14 cases undergoing liver transplantation, 1 case died from jejunum ulcer perforation leading to severe septic shock. Other early complications after operation included intraabdominal infection 3 man-times, virus infection 6 man-times, retrograde infection of biliary 3 man-times, chyle leakage 2 man-times, biliary leakage 3 man-times, biliary stricture 1 man-times, acute rejection 1 man-times, psychiatric symptom because of FK506 2 man-times. The early complication in infants after liver transplantation is high, especially infection and operative complications. Therefore, prevention and treatment are very important.