Abstract:

BACKGROUND: The number of living donor kidney transplantation is greater than that of cadaveric kidney transplantation in some hospitals, however, the safety, superiority, surgical techniques, as well as the ethical issues of living donor kidney transplantation needs further explored.
OBJECTIVE: To analyze the outcomes of kidney transplantation with different sources of kidney by reviewing clinical experience of the living donor and cadaveric donor kidney transplantation at the same periods.
METHODS: Totally 65 cases received living donor kidney transplantation and 169 cases received cadaveric kidney transplantation from January 2002 to March 2008 in the Organ Transplantation Center, 309 Hospital of Chinese PLA, were collected. The data of recipients with different kidney sources, including gender, age, human leucocyte antigen-matching, surgery status, complications, immunosuppression scheme, kidney function and long-term follow-up were comparatively studied to clarify the clinical significance of living donor kidney transplantation．
RESULTS AND CONCLUSION: All 65 cases of living donor kidney transplantation were successful, and the 1-year patient/graft survival rate was 100%．Cadaveric donor kidney transplantation was successful, 2 of which died of cerebral hemorrhage disease, 6 died of severe lung infection after 1 year, and the 1-year patient/graft survival rate was 95.26%. The living donor kidney transplantation was superior to the cadaveric donor kidney transplantation in complications and 1-year patient/graft survival rate and other factors. Living donor kidney transplantation provides a reliable means for patients with full preparation, good matching, few postoperative complications, and high patient/graft survival rate.